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USAGE:
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DOSE:
Begin with 1 drop of cannabis oil. Usually 1-2 drops at a time are sufficient.
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RISKS:
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INSTAGRAM:
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Nellie Benner: https://www.instagram.com/nelliebenner
Bastiaan Rosman: https://www.instagram.com/bashiaanrosman

CURIOUS ABOUT A DRUG?
Let us know which drug by commenting in the comment section below or by using the hashtag #DrugslabBNN.

ABOUT DRUGSLAB:
Drugslab is an educational YouTube channel about drugs, funded by the Dutch government. On this YouTube channel we, Rens Polman, Nellie Benner and Bastiaan Rosman, will take in the drugs you want us to try. We do this in the name of science so we can show you what the effect of drugs are on the human body. You can suggest any type of drug by commenting in the comment section below the videos or by using the hashtag #drugslab. Besides our weekly experiment, we provide you of safe methods of use, safe doses, the effects, the risks and very useful do’s and don’ts when high on drugs. Given by experienced epicureans. Light it up people, in the name of science! Peace.

ABOUT BNN:
BNN is a Dutch public broadcasting association. The broadcasting association was founded in 1997 by Bart de Graaff. The focus of the broadcasting association lies on reaching teenagers and young adults. BNN produces entertainment and informative television programs, radio programs and feature films. Some of BNN’s programming has dealt controversial issues such as the shortage of organ donors, drugs and sex.

ABOUT SPUITEN EN SLIKKEN:
Drugslab is part of Spuiten en Slikken. Spuiten en Slikken (translated as Shoot and Swallow) is a Dutch program on public television. It is a program about sexuality and drugs that started in 2005. It has been broadcasted since on BNN. The aim of the program is to educate youngsters. In the show discussions about sex and drugs take place with weekly guests. The program also features small reports about certain types of drugs and the effects of them, as well as different aspects of sex.

WARNING:
The following show serves an educational purpose in relation to the use of drugs and the effects of using drugs. It is explicitly not the intention to encourage people to use drugs. The acts seen in this show are performed either by professionals or under the supervision of professionals. Accordingly, BNN-VARA and the producers must insist that no one attempt to recreate or re-enact any activity performed on this show and BNN-VARA will not be liable for any material and/or immaterial damage if people do so!

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Official video for Katy Perry’s “This Is How We Do” directed by Joel Kefali and produced by Jason Colon, Danny Lockwood & Danielle Hinde. Production company – Doomsday Entertainment

Lyrics:
Sipping on rosé, sipping on sun, coming up all lazy
Slow cooking pancakes for my boy, still up, still fresh, as a daisy
Playing ping pong all night long, everything’s on me and then hazy
Chanel this, Chanel that, hell yeah
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Straight stuntin’ ya we do it like that
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This is how we do, yeah, chilling, laid back
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This is how we do, do do, this is how we do

Big hoops, and the room leaves, my click happening, my Maseratti
Said to Barbara, chique, at the super rica, grabbing tacos, checking out hotties
Now we talking astrology, getting our nails did, all Japanese-y
Day drinking at the Wildcats, sucking real bad at Mariah karaoke

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This is no big deal

This one goes out to ladies, at breakfast, in last night’s dress
Uh-huh, I see you
Yo, this goes out to all you kids that still have their cars at the club valet and it’s Tuesday
Yo, shout out to all you kids, buying bottle service, with your rent money
Respect

This goes out to all you people going bed with a ten and waking up with a two
This is how we do
Ha, not me

This is how we do, yeah, chilling, laid back
Straight stuntin’ ya we do it like that
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What? Wait. No, no, no
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The world of cannabis has expanded dramatically over the past few decades, shifting the perception of marijuana from a stigmatized substance to a complex plant with various therapeutic benefits. At the forefront of this evolution are two pivotal cannabinoids: Cannabidiol (CBD) and Tetrahydrocannabinol (THC). While both compounds are derived from the Cannabis sativa plant, they possess distinct properties that significantly influence their utility and legalization across various territories. Understanding these differences becomes crucial for consumers, researchers, and policymakers in navigating the complexities associated with cannabis use.

Cannabinoids, such as CBD and THC, interact with the human body’s endocannabinoid system, a network of receptors and neurotransmitters believed to play a pivotal role in maintaining homeostasis and regulating several physiological functions, including mood, memory, pain sensation, and appetite. However, it’s essential to note that while THC is primarily known for its psychoactive effects, causing the “high” commonly associated with marijuana, CBD is non-psychoactive, which means it does not induce such effects. This fundamental difference sets the stage for their respective applications and societal acceptance.

Both CBD and THC offer therapeutic benefits, but the specific effects and legality of these compounds can vary widely. THC is often used for its pain-relieving properties, but can also lead to alterations in perception and cognition, making it less suitable for all consumers. On the other hand, CBD has gained popularity for its anti-inflammatory and anxiolytic properties without the intoxicating effects of THC, appealing more broadly to those seeking relief without the high. As interest in cannabis continues to expand, a nuanced understanding of these two cannabinoids becomes increasingly vital for informed usage.

The Chemical Structure and Effects of CBD and THC

Cannabidiol (CBD) and Tetrahydrocannabinol (THC) share a similar molecular structure, which is why both interact with the endocannabinoid system in the human body. However, the slight differences in their chemical compositions are responsible for the divergent effects that each cannabinoid induces. Both compounds consist of 21 carbon atoms, 30 hydrogen atoms, and 2 oxygen atoms; the key distinction lies in the arrangement of these atoms and the functional groups attached to their structures. This subtle variance results in differing receptor binding capabilities.

When THC binds to cannabinoid receptors in the brain, particularly CB1 receptors, it triggers a series of neurochemical events that lead to the psychoactive effects users experience. These effects can include euphoria, an altered perception of time, and in some cases, anxiety or paranoia, particularly in larger doses. In contrast, CBD does not bind to the CB1 receptors in the same way. Instead, it appears to interact more broadly with a variety of receptors, including serotonin and vanilloid receptors, which contribute to its anti-anxiety and anti-inflammatory properties. This difference in receptor interaction is crucial in determining the therapeutic potential of each cannabinoid.

The therapeutic effects of each cannabinoid can vary significantly due to their chemical interactions. THC is often utilized for its appetite-stimulant properties, pain relief, and its ability to help with sleep. Conversely, CBD is typically favored for its ability to reduce anxiety, assist with seizures, and offer potential antipsychotic properties. Understanding these biochemical mechanisms is essential for determining the appropriate use of each compound, particularly as research continues to shed light on their respective roles in health and wellness.

Legal Status: Navigating the Regulations Around CBD and THC

The legal landscape surrounding CBD and THC varies widely across regions and jurisdictions, reflecting an ongoing evolution in public policy and perception regarding cannabis. In the United States, for instance, the 2018 Farm Bill legalized hemp-derived CBD at the federal level, provided that it contains less than 0.3% THC, effectively distinguishing legitimate CBD products from those that may be classified as illegal marijuana. As a result, the CBD market has exploded, providing consumers with an array of products ranging from oils and tinctures to edibles and topical applications.

On the flip side, THC’s legal status is far more complicated. Many states have opted to legalize medical and recreational marijuana, allowing THC to be consumed by adults in regulated proportions. However, such laws can vary wildly; what is legal in one state may be illegal in another. In contrast, countries outside the United States have diverse approaches; for instance, Canada has fully legalized marijuana, including both CBD and THC, while other countries maintain strict prohibitions against any form of cannabis consumption.

The legal discrepancies between CBD and THC can impact consumers’ access to health benefits purportedly associated with these cannabinoids. Institutions and industries are undergoing transformations as they adapt to the evolving legal environment, making it increasingly essential for consumers to stay informed about the status of these cannabinoids in their specific regions. Moreover, the challenge of navigating these laws may lead consumers to authenticated sources of information to ensure they remain compliant while accessing the benefits of cannabis.

Potential Health Benefits: Exploring Therapeutic Uses

Both CBD and THC are associated with a myriad of health benefits, albeit through different mechanisms. Research has suggested that CBD may play a significant role in managing anxiety and depression, particularly due to its influence on serotonin receptors. Several clinical studies have highlighted CBD’s potential in reducing anxiety in individuals with social anxiety disorder and generalized anxiety, showcasing its therapeutic implications without the psychoactive effects that THC may impose. Additionally, CBD is recognized for its anti-inflammatory properties, making it an attractive option for those suffering from conditions such as arthritis and multiple sclerosis.

Conversely, THC demonstrates promise for pain management. Its psychoactive effects can counteract the perception of pain, making it a viable option for patients with chronic pain conditions or those undergoing treatments such as chemotherapy, where nausea and appetite loss are prevalent. Several studies have found that THC can enhance appetite and alleviate nausea, contributing to a better quality of life for individuals facing debilitating illnesses. Additionally, some evidence suggests that THC may possess neuroprotective qualities, with potential applications in treating neurodegenerative diseases like Alzheimer’s and Parkinson’s.

Moreover, the entourage effect—a phenomenon wherein multiple cannabis compounds work synergistically—suggests that combining CBD and THC may yield enhanced therapeutic benefits. Patients seeking relief from symptoms of conditions such as epilepsy have reported improved outcomes when utilizing cannabis products containing both cannabinoids. While both CBD and THC can be used individually, their combined effects may result in a more favorable therapeutic profile, underscoring the importance of further research into their synergistic potential.

Side Effects and Considerations When Using CBD and THC

Understanding the potential side effects associated with both CBD and THC is crucial for users seeking to maximize benefits while minimizing adverse reactions. While CBD is generally regarded as safe and well-tolerated, some users may experience mild side effects, including drowsiness, dry mouth, or gastrointestinal disturbances. It’s important for users to consult healthcare professionals before starting any CBD regimen, especially if they are on other medications that could interact adversely. Additionally, the lack of FDA regulation on many CBD products raises concerns regarding product quality and consistency.

In contrast, THC is associated with a range of more pronounced side effects due to its psychoactive properties. Users may experience increased heart rate, anxiety, altered judgment, and potential impairments in motor skills and cognitive function. These effects can pose challenges for tasks requiring full concentration, such as driving or operating machinery. Therefore, those seeking to use THC should be mindful of the dose and potency, opting for lower doses to mitigate potential adverse reactions, particularly if they are inexperienced users.

Moreover, the long-term implications of using THC remain a topic of ongoing research. While short-term benefits may be evident for conditions such as chronic pain, the risk of dependency and the psychological effects of prolonged use warrant consideration. Users must make informed decisions based on their personal health conditions, preferences, and legal regulations. Awareness of both cannabinoids’ side effects, along with consultation from healthcare professionals, is key to navigating the complex landscape of cannabis consumption safely.

FAQ: Addressing Common Queries About CBD and THC

As the public’s understanding of CBD and THC continues to grow, several frequently asked questions arise that highlight people’s concerns and curiosities surrounding these cannabinoids. One common question pertains to the legality of these compounds. As mentioned earlier, while CBD is federally legal when derived from hemp, THC’s legality often depends on state regulations. It’s essential for consumers to be aware of the laws governing these cannabinoids in their regions, especially as legislative changes occur rapidly.

Another prevalent inquiry relates to the safety and efficacy of these substances. While both CBD and THC have undergone various studies, consumers should approach their use with caution. The lack of comprehensive FDA regulations can lead to concerns over product quality, necessitating a keen eye for third-party testing and transparent ingredient lists. Additionally, potential users should consult healthcare professionals to ensure they are making informed choices based on individual health needs.

Lastly, many individuals wonder about the differences in effects between CBD and THC. It’s crucial to recognize that while they stem from the same plant, their psychoactive properties and therapeutic applications are notably different. CBD offers relief without intoxication, making it appealing for those who wish to avoid the high that accompanies THC. Acknowledging these differentiating factors can better equip consumers in their search for the right product to meet their therapeutic needs.

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Dr. Lindsey Elmore is a speaker, author, podcast host and world-renowned wellness expert. Dr. Elmore obtained an undergraduate degree in chemistry from the University of Alabama, Birmingham and a doctorate in pharmacy from the University of California San Francisco. She completed her first-year post-doctoral residency in pharmacy practice at Princeton Baptist Medical Center in Birmingham, AL and her second-year specialty residency in ambulatory care at New Hanover Regional Medical Center in Wilmington, NC. She is a Board-Certified Pharmacotherapy Specialist and licensed to practice in three states. She is a Certified 250-hour vinyasa, yin, and Aroma Yoga® Instructor and an Aroma Freedom practitioner. Dr. Elmore has spoken to audiences on five continents and more than 30 countries. She is published in a wide variety of pharmacy and medical journals, is the author of 2 books, and has been quoted in Bustle, Elite Daily, Reader’s Digest, Yahoo News, Parade, MSN, Brit+ Co, Business Insider and more. She has been featured on news segments on NBC, ABC, CBS, Fox,CW, and the Daily Buzz.

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